Glycoconjugates of gadolinium complexes for MRI applications

被引：79

作者：

Fulton, DA

Elemento, EM

Aime, S

Chaabane, L

Botta, M

Parker, D

机构：

[1] Univ Durham, Dept Chem, Durham DH1 3LE, England

[2] Univ Turin, Dipartimento Chim IFM, I-10125 Turin, Italy

[3] CNRS, Lab RMN, UMR 5012, F-69622 Villeurbanne, France

[4] Univ Piemonte Orientale, Dipartimento Sci Ambiente Vita, I-15100 Alessandria, Italy

来源：

CHEMICAL COMMUNICATIONS | 2006年 / 10期

基金：

英国工程与自然科学研究理事会;

关键词：

D O I：

10.1039/b517997a

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Examples of C-4 symmetric, medium MW conjugates incorporating 12 glucose or galactose groups linked via four dendritic wedges to a central Gd complex have been characterised; their enhanced relaxivity is interpreted in terms of effective motional coupling and large contributions from second sphere water molecules.

引用

收藏

页码：1064 / 1066

页数：3

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