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Macrolactonizations in the total synthesis of natural products

被引：419
作者：
Parenty, A
Moreau, X
Campagne, JM
机构：
[1] Ecole Normale Super Chim, F-34296 Montpellier, France
[2] Inst Chim Subst Nat, F-91198 Gif Sur Yvette, France
来源：
CHEMICAL REVIEWS | 2006年 / 106卷 / 03期
关键词：
D O I：
10.1021/cr0301402
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Macrocyclic lactones are lactones with more than 8 atoms in the ring. This paper presents an overview of the macrolactonization of seco-acids in the total synthesis of natural products. Topics discussed are the basics of macrolactonization, macrolactonizations through "acid" activation, and macrolactonizations by "alcohol" activation.
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页码：911 / 939
页数：29
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