Fabrication of polymeric microparticles for drug delivery by soft lithography

被引：81

作者：

Guan, JJ

Ferrell, N

Lee, LJ

Hansford, DJ

机构：

[1] Ohio State Univ, Dept Biomed Engn, Columbus, OH 43210 USA

[2] Ohio State Univ, Dept Chem & Biomol Engn, Columbus, OH 43210 USA

来源：

BIOMATERIALS | 2006年 / 27卷 / 21期

基金：

美国国家科学基金会;

关键词：

drug delivery; soft lithography; microfabrication; microparticle;

D O I：

10.1016/j.biomaterials.2006.03.011

中图分类号：

R318 [生物医学工程];

学科分类号：

0831 ;

摘要：

Soft lithographic techniques were used to fabricate polymeric microparticles for drug delivery applications. The microparticles were made of thermoplastics and thermosets from different types of precursors including reactive resin and polymer solutions in organic solvents or water. The microparticles produced using these methods were made of widely used polymers for drug delivery with highly uniform sizes, plate-like morphology, and well-defined lateral sizes and shapes, making them potentially useful for drug delivery applications and as platform for the construction of multi-functional drug delivery devices. (c) 2006 Elsevier Ltd. All rights reserved.

引用

页码：4034 / 4041

页数：8

共 24 条

[1] Bioadhesive microdevices with multiple reservoirs: a new platform for oral drug delivery [J].