Regioselective, nucleophilic carbon-carbon bond formation at the C4-position of indoles initiated by the aromatic Pummerer-type reaction

被引：42

作者：

Akai, S ^{[1
]}

Kawashita, N ^{[1
]}

Wada, Y ^{[1
]}

Satoh, H ^{[1
]}

Alinejad, AH ^{[1
]}

Kakiguchi, K ^{[1
]}

Kuriwaki, I ^{[1
]}

Kita, Y ^{[1
]}

机构：

[1] Osaka Univ, Grad Sch Pharmaceut Sci, Suita, Osaka 5650871, Japan

来源：

TETRAHEDRON LETTERS | 2006年 / 47卷 / 12期

关键词：

aromatic Pummerer-type reaction; indole; carbon-carbon bond formation; nucleophilic reaction;

D O I：

10.1016/j.tetlet.2006.01.090

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The treatment of the 5-(phenylsulfinyl) in doles with trifluoroacetic anhydride in the presence of carbon nucleophiles achieved the title reactions with complete regioselectivity. (c) 2006 Elsevier Ltd. All rights reserved.

引用

页码：1881 / 1884

页数：4

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