Extending pummerer reaction chemistry.: Synthesis of (±)-dibromophakellstatin by oxidative cyclization of an imidazole derivative

被引：63

作者：

Feldman, KS ^{[1
]}

Skoumbourdis, AP ^{[1
]}

机构：

[1] Penn State Univ, Dept Chem, University Pk, PA 16802 USA

来源：

ORGANIC LETTERS | 2005年 / 7卷 / 05期

关键词：

D O I：

10.1021/ol0500113

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The diastereoselective oxidative cyclization of a dihydrooroiclin derivative is reported. The thioimidate product formed by application of a new variant of the Pummerer reaction serves as a precursor to dibromophakellstatin.

引用

页码：929 / 931

页数：3

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