Moving targets: rapid evolution of oomycete effectors

被引：14

作者：

Soanes, Darren M. ^{[1
]}

Talbot, Nicholas J. ^{[1
]}

机构：

[1] Univ Exeter, Sch Biosci, Exeter EX4 4QD, Devon, England

来源：

TRENDS IN MICROBIOLOGY | 2008年 / 16卷 / 11期

关键词：

D O I：

10.1016/j.tim.2008.08.002

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Plant pathogenic microbes secrete proteins known as effectors, which enter the cytoplasm of plant cells and suppress host defences. Known effectors in oomycete pathogens possess an RXLR-EER motif in their amino acid sequence that is necessary for transport of the effector into a host plant cell. A large number of putative effectors have now been identified in oomycete genomes, the sequences of which show evidence of diversifying selection at their C terminus. Here, we describe recent progress in characterizing RXLR-EER effectors and discuss why so many of these rapidly evolving proteins are encoded by the genomes of plant pathogenic oomycetes.

引用

页码：507 / 510

页数：4

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