A short synthesis of (±)-epiasarinin

被引：22

作者：

Aldous, DJ

Dalençon, AJ

Steel, PG

机构：

[1] Univ Durham, Dept Chem, Durham DH1 3LE, England

[2] Aventis Pharma Inc, Bridgewater, NJ 08807 USA

来源：

ORGANIC LETTERS | 2002年 / 4卷 / 07期

关键词：

D O I：

10.1021/ol025569e

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

[GRAPHICS] Epiasarinin, an endo-endo furofuran, has been synthesized from piperonal via a five-step route with good stereocontrol. The sequence involves Darzens condensation, alkenyl epoxide-dihydrofuran rearrangement, and a Lewis acid mediated cyclization.

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页码：1159 / 1162

页数：4

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