Catalytic asymmetric aldol reactions in water using a chiral Lewis-acid-surfactant-combined catalyst

被引:83
作者
Kobayashi, S [1 ]
Mori, Y [1 ]
Nagayama, S [1 ]
Manabe, K [1 ]
机构
[1] Univ Tokyo, Grad Sch Pharmaceut Sci, Japan Sci & Technol Corp, CREST,Bunkyo Ku, Tokyo 1130033, Japan
关键词
D O I
10.1039/a904439f
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
Catalytic asymmetric aldol reactions in water without the use of organic solvents have been carried out by using a combination of copper bis(dodecyl sulfate), a chiral bis(oxazoline) ligand, and a carboxylic acid to afford the desired products in high yields with good enantiomeric excesses.
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页码:175 / 177
页数:3
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