学术探索
学术期刊
新闻热点
数据分析
智能评审

New concepts in immunology relevant to idiosyncratic drug reactions: The "danger hypothesis" and innate immune system

被引：226
作者：
Uetrecht, JP
机构：
[1] Univ Toronto, Fac Pharm, Toronto, ON M5S 2S2, Canada
[2] Univ Toronto, Fac Med, Toronto, ON M5S 2S2, Canada
来源：
CHEMICAL RESEARCH IN TOXICOLOGY | 1999年 / 12卷 / 05期
关键词：
D O I：
10.1021/tx980249i
中图分类号：
R914 [药物化学];
学科分类号：
100701 ;
摘要：
[No abstract available]
引用
收藏
页码：387 / 395
页数：9
相关论文
共 90 条
  • [11] Claas F H, 1992, Drug Saf, V7 Suppl 1, P3
  • [12] A dose-dependent increase in mortality with vesnarinone among patients with severe heart failure
    Cohn, JN
    Goldstein, SO
    Greenberg, BH
    Lorell, BH
    Bourge, RC
    Jaski, BE
    Gottlieb, SO
    McGrew, F
    DeMets, DL
    White, BG
    [J]. NEW ENGLAND JOURNAL OF MEDICINE, 1998, 339 (25) : 1810 - 1816
  • [13] Cribb AE, 1997, J PHARMACOL EXP THER, V282, P1064
  • [14] Davies D., 1985, TXB ADVERSE DRUG REA, P18
  • [15] LYMPHOCYTE-TRANSFORMATION TEST IN DETECTION OF DRUG HYPERSENSITIVITY
    DOBOZY, A
    HUNYADI, J
    SZKENDERESSY, A
    SIMON, N
    [J]. CLINICAL AND EXPERIMENTAL DERMATOLOGY, 1981, 6 (04) : 367 - 372
  • [16] SEVERE NEUTROPENIA ASSOCIATED WITH SUSTAINED-RELEASE PROCAINAMIDE
    ELLRODT, AG
    MURATA, GH
    RIEDINGER, MS
    STEWART, ME
    MOCHIZUKI, C
    GRAY, R
    [J]. ANNALS OF INTERNAL MEDICINE, 1984, 100 (02) : 197 - 201
  • [17] Elements of immunity - The instructive role of innate immunity in the acquired immune response
    Fearon, DT
    Locksley, RM
    [J]. SCIENCE, 1996, 272 (5258) : 50 - 54
  • [18] AGRANULOCYTOSIS INDUCED BY PROPYLTHIOURACIL - EVIDENCE OF A DRUG DEPENDENT ANTIBODY REACTING WITH GRANULOCYTES, MONOCYTES AND HEMATOPOIETIC PROGENITOR CELLS
    FIBBE, WE
    CLAAS, FHJ
    VANDERSTARDIJKSTRA, W
    SCHAAFSMA, MR
    MEYBOOM, RHB
    FALKENBURG, JHF
    [J]. BRITISH JOURNAL OF HAEMATOLOGY, 1986, 64 (02) : 363 - 373
  • [19] SAFETY AND EFFICACY OF SULFAMETHOXAZOLE AND TRIMETHOPRIM CHEMOPROPHYLAXIS FOR PNEUMOCYSTIS-CARINII PNEUMONIA IN AIDS
    FISCHL, MA
    DICKINSON, GM
    LAVOIE, L
    [J]. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 1988, 259 (08): : 1185 - 1189
  • [20] CHARACTERIZATION OF THE MICROSOMAL EPOXIDE HYDROLASE GENE IN PATIENTS WITH ANTICONVULSANT ADVERSE DRUG-REACTIONS
    GAEDIGK, A
    SPIELBERG, SP
    GRANT, DM
    [J]. PHARMACOGENETICS, 1994, 4 (03): : 142 - 153
123456789