A short cut for the immune system

被引：2

作者：

Brannigan, JA

Dodson, GG

机构：

[1] Chemistry Department University of York,Protein Structure Group

来源：

NATURE STRUCTURAL BIOLOGY | 1997年 / 4卷 / 05期

关键词：

D O I：

10.1038/nsb0597-334

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The crystal structure of the yeast 20S proteasome not only provides further detail of the maws of this family of protein shredders, but also, has profound implications for the mechanism of peptide processing for antigen presentation.

引用

页码：334 / 338

页数：5

共 36 条

[1] Processive degradation of proteins and other catalytic properties of the proteasome from Thermoplasma acidophilum [J].

Akopian, TN ;

Kisselev, AF ;

Goldberg, AL .

JOURNAL OF BIOLOGICAL CHEMISTRY, 1997, 272 (03) :1791-1798

[2] The proteasome [J].

Baumeister, W ;

Lupas, A .

CURRENT OPINION IN STRUCTURAL BIOLOGY, 1997, 7 (02) :273-278

[3] A PROTEIN CATALYTIC FRAMEWORK WITH AN N-TERMINAL NUCLEOPHILE IS CAPABLE OF SELF-ACTIVATION [J].

BRANNIGAN, JA ;

DODSON, G ;

DUGGLEBY, HJ ;

MOODY, PCE ;

SMITH, JL ;

TOMCHICK, DR ;

MURZIN, AG .

NATURE, 1995, 378 (6555) :416-419

[4] Cleavage of pro-X and glu-X bonds catalyzed by the branched chain amino acid preferring activity of the bovine pituitary multicatalytic proteinase complex (20S proteasome) [J].

Cardozo, C ;

Chen, WE ;

Wilk, S .

ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS, 1996, 334 (01) :113-120

[5] Autocatalytic subunit processing couples active site formation in the 20S proteasome to completion of assembly [J].

Chen, P ;

Hochstrasser, M .

CELL, 1996, 86 (06) :961-972

[6] BIOGENESIS, STRUCTURE AND FUNCTION OF THE YEAST 20S PROTEASOME [J].

CHEN, P ;

HOCHSTRASSER, M .

EMBO JOURNAL, 1995, 14 (11) :2620-2630

[7] THE UBIQUITIN-PROTEASOME PROTEOLYTIC PATHWAY [J].

CIECHANOVER, A .

CELL, 1994, 79 (01) :13-21

[8] Structure and functions of the 20S and 26S proteasomes [J].

Coux, O ;

Tanaka, K ;

Goldberg, AL .

ANNUAL REVIEW OF BIOCHEMISTRY, 1996, 65 :801-847

[9] PENICILLIN ACYLASE HAS A SINGLE-AMINO-ACID CATALYTIC CENTER [J].

DUGGLEBY, HJ ;

TOLLEY, SP ;

HILL, CP ;

DODSON, EJ ;

DODSON, G ;

MOODY, PCE .

NATURE, 1995, 373 (6511) :264-268

[10] INHIBITION OF PROTEASOME ACTIVITIES AND SUBUNIT-SPECIFIC AMINO-TERMINAL THREONINE MODIFICATION BY LACTACYSTIN [J].

FENTEANY, G ;

STANDAERT, RF ;

LANE, WS ;

CHOI, S ;

COREY, EJ ;

SCHREIBER, SL .

SCIENCE, 1995, 268 (5211) :726-731

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