Population distribution of six PCR-amplified loci in Madeira Archipelago (Portugal)

被引:6
作者
Corte-Real, F
Souto, L
Anjos, MJ
Carvalho, M
Vieira, DN
Carracedo, A
Vide, MC
机构
[1] Univ Coimbra, Fac Med, Inst Legal Med, P-3000 Coimbra, Portugal
[2] Univ Santiago, Fac Med, Inst Legal Med, E-15705 Santiago De Compostela, Spain
关键词
short tandem repeats; HUMTH01; HUMVWA31/A; HUMF13A1; HUMFES/FPS; D12S391; HUMFIBRA/FGA; population genetics; Madeira;
D O I
10.1016/S0379-0738(98)00202-3
中图分类号
DF [法律]; D9 [法律]; R [医药、卫生];
学科分类号
0301 ; 10 ;
摘要
Frequency data of the short tandem repeat (STR) loci HUMTH01, HUMVWA31/A, HUMF13A1, HUMFES/FPS, D12S391 and HUMFIBRA/FGA were determined in blood stains obtained from a population of unrelated individuals from the Madeira Archipelago. The observed genotype distribution showed no significant deviation from the Hardy-Weinberg equilibrium and there was no evidence for association of alleles among the six loci. Population data showed a combined discrimination power of 0.9999998 and a chance of exclusion of 0.99597. The frequencies are similar to those of other compared caucasian populations but significant differences were found between the Madeira population and Japanese, Chinese, Greenland Eskimos and Quechua Amerindians. The six loci studied, together proved to be highly discriminating and valuable for forensic cases. (C) 1999 Elsevier Science Ireland Ltd. All rights reserved.
引用
收藏
页码:93 / 99
页数:7
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