What are DNA sequence motifs?

被引：191

作者：

D'haeseleer, P ^{[1
]}

机构：

[1] Lawrence Livermore Natl Lab, Microbial Syst Div, Biosci Directorate, Livermore, CA 94551 USA

来源：

NATURE BIOTECHNOLOGY | 2006年 / 24卷 / 04期

关键词：

D O I：

10.1038/nbt0406-423

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

Sequence motifs are becoming increasingly important in the analysis of gene regulation. How do we define sequence motifs, and why should we use sequence logos instead of consensus sequences to represent them? Do they have any relation with binding affinity? How do we search for new instances of a motif in this sea of DNA?

引用

页码：423 / 425

页数：3

共 10 条

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