Dose-dependent killing of leukemia cells by low-temperature plasma

被引：110

作者：

Barekzi, N. ^{[1
]}

Laroussi, M. ^{[1
]}

机构：

[1] Old Dominion Univ, Laser & Plasma Engn Inst, Norfolk, VA 23529 USA

来源：

JOURNAL OF PHYSICS D-APPLIED PHYSICS | 2012年 / 45卷 / 42期

关键词：

ATMOSPHERIC ARGON PLASMA; NONTHERMAL PLASMA; CHRONIC WOUNDS; PRESSURE; INACTIVATION;

D O I：

10.1088/0022-3727/45/42/422002

中图分类号：

O59 [应用物理学];

学科分类号：

070305 [高分子化学与物理];

摘要：

The effect of low-temperature atmospheric pressure plasma towards the progression of cancerous human T-cell leukemia cells was investigated. The plasma pencil, which utilizes short duration high voltage pulses, was used to generate a low-temperature plasma (LTP) plume in ambient air. Our data showed that cell morphology and cell viability were affected in a dose-dependent manner after treatment with LTP. The outcome of this study revealed that the effect of plasma exposure was not immediate, but had a delayed effect and increasing the time of plasma exposure resulted in increased leukemia cell death.

引用

页数：6

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