Ancient DNA Reveals Key Stages in the Formation of Central European Mitochondrial Genetic Diversity

被引：214

作者：

Brandt, Guido ^{[1
]}

Haak, Wolfgang ^{[2
]}

Adler, Christina J. ^{[3
]}

Roth, Christina ^{[1
]}

Szecsenyi-Nagy, Anna ^{[1
]}

Karimnia, Sarah ^{[1
]}

Moeller-Rieker, Sabine ^{[1
]}

Meller, Harald ^{[4
]}

Ganslmeier, Robert ^{[4
]}

Friederich, Susanne ^{[4
]}

Dresely, Veit ^{[4
]}

Nicklisch, Nicole ^{[1
]}

Pickrell, Joseph K. ^{[5
]}

Sirocko, Frank ^{[6
]}

Reich, David ^{[5
]}

Cooper, Alan ^{[2
]}

Alt, Kurt W. ^{[1
]}

机构：

[1] Johannes Gutenberg Univ Mainz, Inst Anthropol, D-55128 Mainz, Germany

[2] Univ Adelaide, Australian Ctr Ancient DNA, Adelaide, SA 5005, Australia

[3] Univ Sydney, Westmead Millennium Inst, Fac Dent, Inst Dent Res, Sydney, NSW 5006, Australia

[4] State Off Heritage Management & Archaeol Saxony A, D-06114 Halle, Saale, Germany

[5] Harvard Univ, Sch Med, Dept Genet, Boston, MA 02115 USA

[6] Johannes Gutenberg Univ Mainz, Inst Geosci, D-55128 Mainz, Germany

来源：

SCIENCE | 2013年 / 342卷 / 6155期

基金：

美国国家科学基金会;

关键词：

HUNTER-GATHERERS; ORIGINS;

D O I：

10.1126/science.1241844

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

The processes that shaped modern European mitochondrial DNA (mtDNA) variation remain unclear. The initial peopling by Palaeolithic hunter-gatherers similar to 42,000 years ago and the immigration of Neolithic farmers into Europe similar to 8000 years ago appear to have played important roles but do not explain present-day mtDNA diversity. We generated mtDNA profiles of 364 individuals from prehistoric cultures in Central Europe to perform a chronological study, spanning the Early Neolithic to the Early Bronze Age (5500 to 1550 calibrated years before the common era). We used this transect through time to identify four marked shifts in genetic composition during the Neolithic period, revealing a key role for Late Neolithic cultures in shaping modern Central European genetic diversity.

引用

页码：257 / 261

页数：5

共 23 条

[1] The molecular dissection of mtDNA haplogroup H confirms that the Franco-Cantabrian glacial refuge was a major source for the European gene pool [J].

Achilli, A ;

Rengo, C ;

Magri, C ;

Battaglia, V ;

Olivieri, A ;

Scozzari, R ;

Cruciani, F ;

Zeviani, M ;

Briem, E ;

Carelli, V ;

Moral, P ;

Dugoujon, JM ;

Roostalu, U ;

Loogväli, EL ;

Kivisild, T ;

Bandelt, HJ ;

Richards, M ;

Villems, R ;

Santachiara-Benerecetti, AS ;

Semino, O ;

Torroni, A .

AMERICAN JOURNAL OF HUMAN GENETICS, 2004, 75 (05) :910-918

[2]

Ammerman AJ., 1984, The Neolithic Transition and the Genetics of Populations in Europe

[3]

Behrens H., 1973, VEROFFENTLICHUNGEN L, V27

[4]

Bogucki P., 2004, Ancient Europe 8000 BC - AD 1000, VII.

[5] Genetic Discontinuity Between Local Hunter-Gatherers and Central Europe's First Farmers [J].

Bramanti, B. ;

Thomas, M. G. ;

Haak, W. ;

Unterlaender, M. ;

Jores, P. ;

Tambets, K. ;

Antanaitis-Jacobs, I. ;

Haidle, M. N. ;

Jankauskas, R. ;

Kind, C. -J. ;

Lueth, F. ;

Terberger, T. ;

Hiller, J. ;

Matsumura, S. ;

Forster, P. ;

Burger, J. .

SCIENCE, 2009, 326 (5949) :137-140

[6] Neolithic mitochondrial haplogroup H genomes and the genetic origins of Europeans [J].

Brotherton, Paul ;

Haak, Wolfgang ;

Templeton, Jennifer ;

Brandt, Guido ;

Soubrier, Julien ;

Adler, Christina Jane ;

Richards, Stephen M. ;

Sarkissian, Clio Der ;

Ganslmeier, Robert ;

Friederich, Susanne ;

Dresely, Veit ;

van Oven, Mannis ;

Kenyon, Rosalie ;

Van der Hoek, Mark B. ;

Korlach, Jonas ;

Luong, Khai ;

Ho, Simon Y. W. ;

Quintana-Murci, Lluis ;

Behar, Doron M. ;

Meller, Harald ;

Alt, Kurt W. ;

Cooper, Alan .

NATURE COMMUNICATIONS, 2013, 4

[7]

Cunliffe BarryW., 2008, Europe Between the Oceans: Themes and Variations, 9000 BC - AD 1000

[8] Ancient DNA Reveals Prehistoric Gene-Flow from Siberia in the Complex Human Population History of North East Europe [J].

Sarkissian, Clio Der ;

Balanovsky, Oleg ;

Brandt, Guido ;

Khartanovich, Valery ;

Buzhilova, Alexandra ;

Koshel, Sergey ;

Zaporozhchenko, Valery ;

Gronenborn, Detlef ;

Moiseyev, Vyacheslav ;

Kolpakov, Eugen ;

Shumkin, Vladimir ;

Alt, Kurt W. ;

Balanovska, Elena ;

Cooper, Alan ;

Haak, Wolfgang .

PLOS GENETICS, 2013, 9 (02)

[9] A Revised Timescale for Human Evolution Based on Ancient Mitochondrial Genomes [J].

Fu, Qiaomei ;

Mittnik, Alissa ;

Johnson, Philip L. F. ;

Bos, Kirsten ;

Lari, Martina ;

Bollongino, Ruth ;

Sun, Chengkai ;

Giemsch, Liane ;

Schmitz, Ralf ;

Burger, Joachim ;

Ronchitelli, Anna Maria ;

Martini, Fabio ;

Cremonesi, Renata G. ;

Svoboda, Jiri ;

Bauer, Peter ;

Caramelli, David ;

Castellano, Sergi ;

Reich, David ;

Paeaebo, Svante ;

Krause, Johannes .

CURRENT BIOLOGY, 2013, 23 (07) :553-559

[10] Ancient DNA from an Early Neolithic Iberian population supports a pioneer colonization by first farmers [J].

Gamba, C. ;

Fernandez, E. ;

Tirado, M. ;

Deguilloux, M. F. ;

Pemonge, M. H. ;

Utrilla, P. ;

Edo, M. ;

Molist, M. ;

Rasteiro, R. ;

Chikhi, L. ;

Arroyo-Pardo, E. .

MOLECULAR ECOLOGY, 2012, 21 (01) :45-56

← 1 2 3 →