PAMAM dendrimers for efficient siRNA delivery and potent gene silencing

被引：283

作者：

Zhou, Jiehua

Wu, Jiangyu

Hafdi, Nadia

Behr, Jean-Paul

Erbacher, Patrick

Peng, Ling ^{[1
]}

机构：

[1] Wuhan Univ, Coll Chem & Mol Sci, Wuhan 430072, Peoples R China

[2] CNRS, UMR 6114, Dept Chim, F-13288 Marseille 09, France

[3] Polyplus Transfect SA, F-67401 Illkirch Graffenstaden, France

[4] Fac Pharm, CNRS, Lab Chim Genet, F-67401 Illkirch Graffenstaden, France

来源：

CHEMICAL COMMUNICATIONS | 2006年 / 22期

关键词：

D O I：

10.1039/b601381c

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Genuine, nondegraded PAMAM dendrimers self-assemble with siRNA into nanoscale particles that are efficient for siRNA delivery and induce potent endogenous gene silencing.

引用

页码：2362 / 2364

页数：3

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