A novel and versatile computational tool to model translation

被引：16

作者：

Chu, Dominique ^{[1
]}

Zabet, Nicolae ^{[2
]}

von der Haar, Tobias ^{[3
]}

机构：

[1] Univ Kent, Sch Comp, Canterbury CT2 7NF, Kent, England

[2] Univ Cambridge, Dept Genet, Cambridge CB2 1QR, England

[3] Univ Kent, Sch Biosci, Canterbury CT2 7NJ, Kent, England

来源：

BIOINFORMATICS | 2012年 / 28卷 / 02期

基金：

英国生物技术与生命科学研究理事会;

关键词：

TRANSFER-RNA; SACCHAROMYCES-CEREVISIAE; RIBOSOME; COMPETITION; FIDELITY;

D O I：

10.1093/bioinformatics/btr650

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

Software: In this application note, we present a novel, highly efficient software tool to model translation. The tool represents the main aspects of translation. Features include a representation of exhaustible tRNA pools, ribosome-ribosome interactions and differential initiation rates for different mRNA species. The tool is written in Java, and is hence portable and can be parameterized for any organism.

引用

页码：292 / 293

页数：2

共 8 条

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