UniProt: a worldwide hub of protein knowledge

被引：4210

作者：

Bateman, Alex ^{[1
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Martin, Maria-Jesus ^{[1
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Orchard, Sandra ^{[1
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Magrane, Michele ^{[1
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Alpi, Emanuele ^{[1
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Bely, Benoit ^{[1
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Bingley, Mark ^{[1
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Britto, Ramona ^{[1
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Bursteinas, Borisas ^{[1
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Busiello, Gianluca ^{[1
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Bye-A-Jee, Hema ^{[1
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Da Silva, Alan ^{[1
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De Giorgi, Maurizio ^{[1
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Dogan, Tunca ^{[1
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Castro, Leyla Garcia ^{[1
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Garmiri, Penelope ^{[1
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Georghiou, George ^{[1
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Gonzales, Daniel ^{[1
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Gonzales, Leonardo ^{[1
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Hatton-Ellis, Emma ^{[1
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Ignatchenko, Alexandr ^{[1
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Ishtiaq, Rizwan ^{[1
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Jokinen, Petteri ^{[1
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Joshi, Vishal ^{[1
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Jyothi, Dushyanth ^{[1
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Lopez, Rodrigo ^{[1
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Luo, Jie ^{[1
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Lussi, Yvonne ^{[1
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MacDougall, Alistair ^{[1
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Madeira, Fabio ^{[1
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Mahmoudy, Mahdi ^{[1
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Menchi, Manuela ^{[1
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Nightingale, Andrew ^{[1
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Onwubiko, Joseph ^{[1
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Palka, Barbara ^{[1
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Pichler, Klemens ^{[1
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Pundir, Sangya ^{[1
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Qi, Guoying ^{[1
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Raj, Shriya ^{[1
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Renaux, Alexandre ^{[1
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Lopez, Milagros Rodriguez ^{[1
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Saidi, Rabie ^{[1
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Sawford, Tony ^{[1
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Shypitsyna, Aleksandra ^{[1
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Speretta, Elena ^{[1
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Turner, Edward ^{[1
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Tyagi, Nidhi ^{[1
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Vasudev, Preethi ^{[1
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Volynkin, Vladimir ^{[1
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Wardell, Tony ^{[1
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机构：

[1] EBI, EMBL, Wellcome Genome Campus, Cambridge CB10 1SD, England

[2] Ctr Med Univ Geneva, SIB, 1 Rue Michel Servet, CH-1211 Geneva 4, Switzerland

[3] Georgetown Univ, Prot Informat Resource, Med Ctr, 3300 Whitehaven St NW,Suite 1200, Washington, DC 20007 USA

[4] Univ Delaware, Prot Informat Resource, 15 Innovat Way,Suite 205, Newark, DE 19711 USA

来源：

NUCLEIC ACIDS RESEARCH | 2019年 / 47卷 / D1期

基金：

英国生物技术与生命科学研究理事会; 美国国家卫生研究院;

关键词：

BIOINFORMATICS RESOURCE; DATABASE;

D O I：

10.1093/nar/gky1049

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The UniProt Knowledgebase is a collection of sequences and annotations for over 120 million proteins across all branches of life. Detailed annotations extracted from the literature by expert curators have been collected for over half a million of these proteins. These annotations are supplemented by annotations provided by rule based automated systems, and those imported from other resources. In this article we describe significant updates that we have made over the last 2 years to the resource. We have greatly expanded the number of Reference Proteomes that we provide and in particular we have focussed on improving the number of viral Reference Proteomes. The UniProt website has been augmented with new data visualizations for the subcellular localization of proteins as well as their structure and interactions. UniProt resources are available under a CC-BY (4.0) license via the web at https://www.uniprot.org/.

引用

页码：D506 / D515

页数：10

共 31 条

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