VectorBase: an updated bioinformatics resource for invertebrate vectors and other organisms related with human diseases

被引:421
作者
Giraldo-Calderon, Gloria I. [1 ]
Emrich, Scott J. [2 ,3 ]
MacCallum, Robert M. [4 ]
Maslen, Gareth [5 ]
Dialynas, Emmanuel [6 ]
Topalis, Pantelis [6 ]
Ho, Nicholas [4 ]
Gesing, Sandra [7 ]
Madey, Gregory [2 ,3 ]
Collins, Frank H. [1 ,3 ]
Lawson, Daniel [5 ]
机构
[1] Univ Notre Dame, Dept Biol Sci, Notre Dame, IN 46556 USA
[2] Univ Notre Dame, Dept Comp Sci & Engn, Notre Dame, IN 46556 USA
[3] Univ Notre Dame, ECK Inst Global Hlth, Notre Dame, IN 46556 USA
[4] Univ London Imperial Coll Sci Technol & Med, Dept Life Sci, London SW7 2AZ, England
[5] European Bioinformat Inst EMBL EBI, European Mol Biol Lab, Cambridge CB10 1SD, England
[6] FORTH, IMBB, Iraklion 70013, Crete, Greece
[7] Univ Notre Dame, Ctr Res Comp, Notre Dame, IN 46556 USA
基金
美国国家卫生研究院;
关键词
ANOPHELES-GAMBIAE; ANNOTATION; ONTOLOGIES; MALARIA; EXPRESSION; MANAGEMENT; SPECIATION; SOFTWARE; MAP;
D O I
10.1093/nar/gku1117
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
VectorBase is a National Institute of Allergy and Infectious Diseases supported Bioinformatics Resource Center (BRC) for invertebrate vectors of human pathogens. Now in its 11th year, VectorBase currently hosts the genomes of 35 organisms including a number of non-vectors for comparative analysis. Hosted data range from genome assemblies with annotated gene features, transcript and protein expression data to population genetics including variation and insecticide-resistance phenotypes. Here we describe improvements to our resource and the set of tools available for interrogating and accessing BRC data including the integration of Web Apollo to facilitate community annotation and providing Galaxy to support user-based workflows. VectorBase also actively supports our community through hands-on workshops and online tutorials. All information and data are freely available from our website at https://www.vectorbase.org/.
引用
收藏
页码:D707 / D713
页数:7
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