Solubility of Podophyllotoxin in Six Organic Solvents from (283.2 to 323.2) K

被引:7
作者
Gan, Li-She [1 ]
Wang, Zhen-Zhen [1 ]
Zhou, Chang-Xin [1 ]
机构
[1] Zhejiang Univ, Coll Pharmaceut Sci, Inst Modern Chinese Med, Hangzhou 310058, Zhejiang, Peoples R China
关键词
ACID; ETOPOSIDE;
D O I
10.1021/je8007028
中图分类号
O414.1 [热力学];
学科分类号
070201 [理论物理];
摘要
The solubility of podophyllotoxin (furo[3',4':6,7]naphtho[2,3-d]-1,3-dioxol-6(5aH)-one, 5,8,8a,9-tetrahydro-9-hydroxy-5-(3,4,5-trimethoxyphenyl), (5R,5aR,8aR,9R)) in ethanol, methanol, acetone, ethyl acetate, propan-2-ol, and butan-l-of from (283.2 to 323.2) K was measured under atmospheric pressure. The solubility of podophyllotoxin in these solvents increases with increasing temperature. The solubility values were correlated with the Apelblat equation.
引用
收藏
页码:160 / 161
页数:2
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