Structural and functional modifications in glutamateric synapses following prolonged ethanol exposure

被引:32
作者
Chandler, LJ
Carpenter-Hyland, E
Hendricson, AW
Maldve, RE
Morrisett, RA
Zhou, FC
Sari, Y
Bell, R
Szumlinski, KK
机构
[1] Med Univ S Carolina, Dept Neurosci, Charleston, SC 29425 USA
[2] Med Univ S Carolina, Alcohol Res Ctr, Charleston, SC 29425 USA
[3] Univ Texas, Coll Pharm, Austin, TX 78712 USA
[4] Univ Calif Santa Barbara, Dept Psychol, Santa Barbara, CA 93106 USA
[5] Indiana Univ, Sch Med, Dept Anat & Cell Biol, Indianapolis, IN USA
关键词
ethanol; nucleus accumbens; NMDA receptors; dendritic spines; postsynaptic density; PSD-95; Homer2; seizure; explants; plasticity;
D O I
10.1111/j.1530-0277.2006.00041.x
中图分类号
R194 [卫生标准、卫生检查、医药管理];
学科分类号
摘要
This article summarizes the proceedings of a symposium presented at the 2005 annual meeting of the Research Society on Alcoholism in Santa Barbara, California, USA. The organizer and chair was L. Judson Chandler. The presentations were (1) Chronic Ethanol Exposure, N-Methyl-D-Aspartate (NMDA) Receptor Dynamics, and Withdrawal Hyperexcitability, by Adam Hendricson, Regina Maldve, and Richard Morrisett, (2) Ethanol-Induced Synaptic Targeting of NMDA Receptors Is Associated With Enhanced Postsynaptic Density-95 Clustering and Spine Size, by Judson Chandler and Ezekiel Carpenter-Hyland; (3) Presynaptic and Postsynaptic Alterations in the Nucleus Accumbens Following Chronic Alcohol Exposure, by Feng Zhou, Youssef Sari, and Richard Bell;, and (4) An Active Role for Accumbens Homer2 Expression in Alcohol-Induced Neural Plasticity, by Karen Szumlinski.
引用
收藏
页码:368 / 376
页数:9
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