Lipophilicity profiles: Theory and measurement

被引：98

作者：

Comer, J ^{[1
]}

Tam, K ^{[1
]}

机构：

[1] Sirius Analyt Instruments Ltd, Forest Row RH18 5HE, E Sussex, England

来源：

PHARMACOKINETIC OPTIMIZATION IN DRUG RESEARCH: BIOLOGICAL, PHYSICOCHEMICAL, AND COMPUTATIONAL STRATEGIES | 2001年

关键词：

D O I：

10.1002/9783906390437.ch17

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

引用

页码：275 / 304

页数：30

共 57 条

[21]

GEMPERLINE PJ, 1990, COMPUTER ENHANCED AN, V2, P27

[22]

GLUCK SJ, 1994, CHROMATOGRAPHIC SERI, P199

[23] PRINCIPLES OF METHOD SELECTION IN PARTITION STUDIES [J].

HERSEY, A ;

HILL, AP ;

HYDE, RM ;

LIVINGSTONE, DJ .

QUANTITATIVE STRUCTURE-ACTIVITY RELATIONSHIPS, 1989, 8 (04) :288-296

[24] PREDICTING 1-OCTANOL-WATER PARTITION-COEFFICIENT BY HIGH-PERFORMANCE LIQUID-CHROMATOGRAPHY GRADIENT ELUTION [J].

KAUNE, A ;

KNORRENSCHILD, M ;

KETTRUP, A .

FRESENIUS JOURNAL OF ANALYTICAL CHEMISTRY, 1995, 352 (3-4) :303-312

[25]

Kramer M, 1998, PC WEEK, V15, P10

[26] Absorption prediction from physicochemical parameters [J].

Krämer, SD .

PHARMACEUTICAL SCIENCE & TECHNOLOGY TODAY, 1999, 2 (09) :373-380

[27]

LIEN EJ, 1995, ENCY PHARM TECHNOLOG, P293

[28] Complete resolution of the ionization equilibria of 5-deoxypyridoxal in water-dioxane mixtures [J].

Llor, J ;

Ros, MP ;

Asensio, SB .

JOURNAL OF SOLUTION CHEMISTRY, 1997, 26 (11) :1021-1036

[29]

Malinowski E.R., 1991, FACTOR ANAL CHEM

[30] DETERMINATION OF NUMBER OF FACTORS AND EXPERIMENTAL ERROR IN A DATA MATRIX [J].

MALINOWSKI, ER .

ANALYTICAL CHEMISTRY, 1977, 49 (04) :612-617

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