Simple procedure for the synthesis of 2,5-bis(silylated)thiophene S-oxides with m-chloroperbenzoic acid in the presence of BF3(Et(2)O)

被引:35
作者
Furukawa, N [1 ]
Zhang, SZ [1 ]
Sato, S [1 ]
Higaki, M [1 ]
机构
[1] UNIV TSUKUBA, DEPT CHEM, TSUKUBA, IBARAKI 305, JAPAN
关键词
D O I
10.3987/COM-95-S1
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
Oxidation of 2,5-bis(silyl)thiophenes (1) with m-chloroperbenzoic acid (m-CPBA) in the presence of BF3(Et(2)O) gave the corresponding S-oxides (2) in moderate yields, while, without BF3(Et(2)O), the oxidation gave solely the corresponding thiophene S-dioxides (3) and no S-oxide was obtained at all. This procedure was successfully applied to the synthesis of other 2,5-bis-substituted thiophene monooxides.
引用
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页码:61 / 66
页数:6
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