Lymphatic absorption of phytosterol oxides in rats

被引：44

作者：

Grandgirard, A

Sergiel, JP

Nour, M

Demaison-Meloche, J

Giniès, C

机构：

[1] INRA, Unite Nutr Lipid, F-21034 Dijon, France

[2] Fac Pharm, Dijon, France

[3] INRA, Rech Aromes Lab, Dijon, France

来源：

LIPIDS | 1999年 / 34卷 / 06期

关键词：

D O I：

10.1007/s11745-999-0399-z

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Two of the main classes of oxyphytosterols (7-keto and epoxides) were synthesized from sitosterol and campesterol and given to mesenteric duct-cannulated adult male rats. Lymph was collected during 24 h and was analyzed for oxysterols. The results showed that the lymphatic recovery of the phytosterol oxides was low: 4.7% of the given dose for epoxy derivatives and 1.5% for 7-keto compounds. The campesterol oxides presented a better absorption than the sitosterol oxides. During the process of absorption, the epoxyphytostanols were also partly transformed in campestanetriol and stigmastanetriol.

引用

页码：563 / 570

页数：8

共 62 条

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