A new chiral oxathiane:: synthesis, resolution and absolute configuration determination by vibrational circular dichroism

被引：20

作者：

Solladié-Cavallo, A

Balaz, M

Salisova, M

Suteu, C

Nafie, LA

Cao, X

Freedman, TB

机构：

[1] Syracuse Univ, Dept Chem, Syracuse, NY 13244 USA

[2] Univ Strasbourg, Lab Stereochim Organomet, CNRS, ECPM, F-67087 Strasbourg, France

[3] Comenius Univ, Dept Organ Chem, Bratislava, Slovakia

[4] Chiral Technol Europe, F-67404 Illkirch Graffenstaden, France

来源：

TETRAHEDRON-ASYMMETRY | 2001年 / 12卷 / 18期

关键词：

D O I：

10.1016/S0957-4166(01)00441-4

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

A new oxathiane, derived from 5-hydroxy-1-tetralone has been synthesized in eight steps, fully characterized as cis-fused rings by 1D and 2D NMR and resolved by preparative chiral chromatography (CHIRALCEL OD-R). The second eluting (+, MeOH)-isomer was assigned (S,S)-configuration by VCD-ab initio simulation. (C) 2001 Elsevier Science Ltd. All rights reserved.

引用

页码：2605 / 2611

页数：7

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[22] A two-step asymmetric synthesis of pure trans-(R,R)-diaryl-epoxides [J].