Analyses of Stemona alkaloids in Stemona tuberosa by liquid chromatography/tandem mass spectrometry

被引：37

作者：

Zhou, Y

Jiang, RW

Hon, PM

Xu, YT

Chan, YM

Chan, TWD

Xu, HX

Ding, LS

But, PPH ^{[1
]}

Shaw, PC

机构：

[1] Chinese Univ Hong Kong, Inst Chinese Med, Shatin, Hong Kong, Peoples R China

[2] Chinese Univ Hong Kong, Dept Biol, Shatin, Hong Kong, Peoples R China

[3] Chinese Univ Hong Kong, Dept Chem, Shatin, Hong Kong, Peoples R China

[4] Chinese Univ Hong Kong, Dept Biochem, Shatin, Hong Kong, Peoples R China

[5] Hong Kong Jockey Club Inst Chinese Med, Shatin, Hong Kong, Peoples R China

[6] Chinese Acad Sci, Chengdu Inst Bot, Chengdu 610041, Sichuan Prov, Peoples R China

来源：

RAPID COMMUNICATIONS IN MASS SPECTROMETRY | 2006年 / 20卷 / 06期

关键词：

21;

D O I：

10.1002/rcm.2409

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

Alkaloid profiles in Stemona tuberosa were found to be highly variable. Six Stemona alkaloids isolated from the plant were subjected to on-line high-performance liquid chromatography/electrospray ionization mass spectrometry (HPLC/ESI-MS) and tandem mass spectrometry (MS/MS) analyses. Their fragmentation patterns and products were useful for their characterization. The LC/MS fingerprints of these alkaloids, though variable among samples, could provide an overall characterization of the authenticity and quality of this species and help to differentiate it from S. japonica and S. sessilifolia, as all three species are recognized as genuine sources of the herb Radix Stemonae in the Pharmacopoeia of the People's Republic of China. Copyright (c) 2006 John Wiley & Sons, Ltd.

引用

页码：1030 / 1038

页数：9