Human granulocytic anaplasmosis

被引:122
作者
Bakken, Johan S. [1 ,2 ]
Dumler, Stephen [3 ]
机构
[1] St Lukes Infect Dis Associates, Duluth, MN 55802 USA
[2] Univ Minnesota, Dept Family Med, Sch Med, Duluth, MN 55202 USA
[3] Johns Hopkins Univ, Sch Med, Div Med Microbiol, Dept Pathol, Baltimore, MD 21205 USA
关键词
D O I
10.1016/j.idc.2008.03.011
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
Tick-borne infections have been recognized in the United States for more than a century. Patients who present with nonspecific fever after exposure to ticks should be evaluated by clinical examination and routine laboratory testing to determine if the illness is potentially a tick-borne infection. This article focuses on the diagnosis and management of human granulocytic anaplasmosis (HGA) caused by Anaplasma phagocytophilum.
引用
收藏
页码:433 / +
页数:17
相关论文
共 86 条
[31]   Anaplasma phagocytophilum ligation to toll-like receptor (TLR) 2, but not to TLR4, activates macrophages for nuclear factor-κB nuclear translocation [J].
Choi, KS ;
Scorpio, DG ;
Dumler, JS .
JOURNAL OF INFECTIOUS DISEASES, 2004, 189 (10) :1921-1925
[32]   Mitogenic component in polar lipid-enriched Anaplasma phagocytophilum membranes [J].
Choi, Kyoung-Seong ;
Dumler, J. Stephen .
CLINICAL AND VACCINE IMMUNOLOGY, 2007, 14 (10) :1260-1265
[33]   Epidemiology of human ehrlichiosis and anaplasmosis in the United States, 2001-2002 [J].
Demma, LJ ;
Holman, RC ;
McQuiston, JH ;
Krebs, JW ;
Swerdlow, DL .
AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE, 2005, 73 (02) :400-409
[34]   Human granulocytic anaplasmosis and macrophage activation [J].
Dumler, J. Stephen ;
Barat, Nicole C. ;
Barat, Christopher E. ;
Bakken, Johan S. .
CLINICAL INFECTIOUS DISEASES, 2007, 45 (02) :199-204
[35]   Ehrlichioses in humans: Epidemiology, clinical presentation, diagnosis, and treatment [J].
Dumler, J. Stephen ;
Madigan, John E. ;
Pusterla, Nicola ;
Bakken, Johan S. .
CLINICAL INFECTIOUS DISEASES, 2007, 45 :S45-S51
[36]   Anaplasma and Ehrlichia infection [J].
Dumler, J. Stephen .
RICKETTSIOSES: FROM GENOME TO PROTEOME, PATHOBIOLOGY, AND RICKETTSIAE AS AN INTERNATIONAL THREAT, 2005, 1063 :361-373
[37]   Human granulocytic anaplasmosis and Anaplasma phagocytophilum [J].
Dumler, JS ;
Choi, KS ;
Garcia-Garcia, JC ;
Barat, NS ;
Scorpio, DG ;
Garyu, JW ;
Grab, DJ ;
Bakken, JS .
EMERGING INFECTIOUS DISEASES, 2005, 11 (12) :1828-1834
[38]   A population-based seroepidemiologic study of human granulocytic ehrlichiosis and Lyme borreliosis on the west coast of Sweden [J].
Dumler, JS ;
Dotevall, L ;
Gustafson, R ;
Granstrom, M .
JOURNAL OF INFECTIOUS DISEASES, 1997, 175 (03) :720-722
[39]  
Dumler JS, 2001, LANCET, P21, DOI 10.1016/S1473-3099(09)70296-8
[40]  
Elston DM, 1998, NEW ENGL J MED, V339, P1941, DOI 10.1056/NEJM199812243392615