Steady-state characterization of systems with moiety-conservations made easy: Matrix equations of metabolic control analysis and biochemical system theory

被引：6

作者：

Cascante, M ^{[1
]}

Puigjaner, J ^{[1
]}

Kholodenko, B ^{[1
]}

机构：

[1] MOSCOW MV LOMONOSOV STATE UNIV, AN BELOZERSKY INST PHYSICOCHEM BIOL, MOSCOW 119898, RUSSIA

来源：

JOURNAL OF THEORETICAL BIOLOGY | 1996年 / 178卷 / 01期

关键词：

D O I：

10.1006/jtbi.1996.0001

中图分类号：

Q [生物科学];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

A set of matrix equations based on the Sensitivity Theory is derived that allows the expression of the global control properties of a pathway as a function of its local properties (and vice versa) by a single matrix inversion. The matrix of the local properties is built up from: (1) the experimentally determined coefficients, (2) a link matrix (which corresponds to the moiety-conservation relationships) and (3) the matrix reflecting the structural properties of the pathway.

引用

页码：1 / 6

页数：6

共 23 条

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