Mycobacterium avium infection and immune restoration disease after highly active antiretroviral therapy in a patient with HIV and normal CD4+ counts

被引:21
作者
Hassell, M
French, MA
机构
[1] Royal Perth Hosp, Dept Clin Immunol & Biochem Genet, Perth, WA 6001, Australia
[2] Royal Perth Hosp, Communicable Dis Serv, Perth, WA 6001, Australia
关键词
D O I
10.1007/s10096-001-0634-8
中图分类号
R51 [传染病];
学科分类号
100401 ;
摘要
A patient infected with HIV who had normal CD4+ T-cell counts developed Mycobacterium avium complex lymphadenitis associated with restoration of delayed-type hypersensitivity responses to mycobacterial antigens after commencing highly active antiretroviral therapy (Mycobacterium avium immune restoration disease). This case provides further evidence that delayed-type hypersensitivity responses and CD4+ T-cell counts are independent indicators of the cellular immune defects induced by HIV infection and that Mycobacterium avium immune restoration disease may occur in patients with persistently normal CD4+ T-cell counts.
引用
收藏
页码:889 / 891
页数:3
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