Impact of Changes in Clostridium difficile Testing Practices on Stool Rejection Policies and C. difficile Positivity Rates across Multiple Laboratories in the United States

被引：27

作者：

Cohen, Jessica ^{[1
,2
]}

Limbago, Brandi ^{[2
]}

Dumyati, Ghinwa ^{[3
]}

Holzbauer, Stacy ^{[4
]}

Johnston, Helen ^{[5
]}

Perlmutter, Rebecca ^{[6
]}

Dunn, John ^{[7
]}

Nadle, Joelle ^{[8
]}

Lyons, Carol ^{[9
]}

Phipps, Erin ^{[10
]}

Beldavs, Zintars ^{[11
]}

Clark, Leigh Ann ^{[12
]}

Lessa, Fernanda C. ^{[2
]}

机构：

[1] Atlanta Res & Educ Fdn, Atlanta, GA 30033 USA

[2] CDC, Div Healthcare Qual Promot, Atlanta, GA 30333 USA

[3] Univ Rochester, Rochester, NY USA

[4] Minnesota Dept Hlth, St Paul, MN USA

[5] Colorado Dept Publ Hlth & Environm, Denver, CO USA

[6] Maryland Dept Hlth & Mental Hyg, Baltimore, MD USA

[7] Tennessee Dept Hlth, Nashville, TN USA

[8] Calif Emerging Infect Program, Oakland, CA USA

[9] Connecticut Emerging Infect Program, New Haven, CT USA

[10] Univ New Mexico, New Mexico Emerging Infect Program, Albuquerque, NM 87131 USA

[11] Oregon Hlth Author, Portland, OR USA

[12] Georgia Emerging Infect Program, Atlanta, GA USA

来源：

JOURNAL OF CLINICAL MICROBIOLOGY | 2014年 / 52卷 / 02期

关键词：

INFECTION; DIAGNOSIS; LIGHT; ASSAY; END; PCR;

D O I：

10.1128/JCM.02177-13

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

We describe the adoption of nucleic acid amplification tests (NAAT) for Clostridium difficile diagnosis and their impact on stool rejection policies and C. difficile positivity rates. Of the laboratories with complete surveys, 51 (43%) reported using NAAT in 2011. Laboratories using NAAT had stricter rejection policies and increased positivity rates.

引用

页码：632 / 634

页数：3

共 18 条

[1] Nonutility of Repeat Laboratory Testing for Detection of Clostridium difficile by Use of PCR or Enzyme Immunoassay [J].

Aichinger, Elisabeth ;

Schleck, Cathy D. ;

Harmsen, William S. ;

Nyre, Lisa M. ;

Patel, Robin .

JOURNAL OF CLINICAL MICROBIOLOGY, 2008, 46 (11) :3795-3797

[2]

[Anonymous], PRACTICAL GUIDANCE D

[3]

[Anonymous], MEAS SCOP CLOSTR DIF

[4] Laboratory Diagnosis of Clostridium difficile Infections: There Is Light at the End of the Colon [J].

Brecher, Stephen M. ;

Novak-Weekley, Susan M. ;

Nagy, Elisabeth .

CLINICAL INFECTIOUS DISEASES, 2013, 57 (08) :1175-1181

[5] Biology of Clostridium difficile: Implications for Epidemiology and Diagnosis [J].

Carroll, Karen C. ;

Bartlett, John G. .

ANNUAL REVIEW OF MICROBIOLOGY, VOL 65, 2011, 65 :501-521

[6] Repeat Stool Testing to Diagnose Clostridium difficile Infection Using Enzyme Immunoassay Does Not Increase Diagnostic Yield [J].

Deshpande, Abhishek ;

Pasupuleti, Vinay ;

Patel, Preethi ;

Ajani, Gati ;

Hall, Geraldine ;

Hu, Bo ;

Jain, Anil ;

Rolston, David D. K. .

CLINICAL GASTROENTEROLOGY AND HEPATOLOGY, 2011, 9 (08) :665-U72

[7] Comparison of Nine Commercially Available Clostridium difficile Toxin Detection Assays, a Real-Time PCR Assay for C. difficile tcdB, and a Glutamate Dehydrogenase Detection Assay to Cytotoxin Testing and Cytotoxigenic Culture Methods [J].

Eastwood, Kerrie ;

Else, Patrick ;

Charlett, Andre ;

Wilcox, Mark .

JOURNAL OF CLINICAL MICROBIOLOGY, 2009, 47 (10) :3211-3217

[8] Public Reporting of Clostridium difficile and Improvements in Diagnostic Tests [J].

Goldenberg, Simon D. .

INFECTION CONTROL AND HOSPITAL EPIDEMIOLOGY, 2011, 32 (12) :1231-1232

[9] Clinical and Laboratory Characteristics of Clostridium difficile Infection in Patients with Discordant Diagnostic Test Results [J].

Kaltsas, Anna ;

Simon, Matt ;

Unruh, Larissa H. ;

Son, Crystal ;

Wroblewski, Danielle ;

Musser, Kimberlee A. ;

Sepkowitz, Kent ;

Babady, N. Esther ;

Kamboj, Mini .

JOURNAL OF CLINICAL MICROBIOLOGY, 2012, 50 (04) :1303-1307

[10] Impact of the Type of Diagnostic Assay on Clostridium difficile Infection and Complication Rates in a Mandatory Reporting Program [J].

Longtin, Yves ;

Trottier, Sylvie ;

Brochu, Gilles ;

Paquet-Bolduc, Bianka ;

Garenc, Christophe ;

Loungnarath, Vilayvong ;

Beaulieu, Catherine ;

Goulet, Danielle ;

Longtin, Jean .

CLINICAL INFECTIOUS DISEASES, 2013, 56 (01) :67-73

← 1 2 →