Solvent-free organic syntheses - using supported reagents and microwave irradiation

被引：1625

作者：

Varma, RS ^{[1
]}

机构：

[1] Sam Houston State Univ, Dept Chem, Huntsville, TX 77341 USA

[2] Sam Houston State Univ, Texas Res Inst Environm Studies, Huntsville, TX 77341 USA

来源：

GREEN CHEMISTRY | 1999年 / 1卷 / 01期

关键词：

D O I：

10.1039/a808223e

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Recent developments in microwave-accelerated solventless organic syntheses are summarised. This expeditious and solvent-free approach involves the exposure of neat reactants to microwave (MW) irradiation in conjunction with the use of supported reagents or catalysts which are primarily of mineral origin. The salient features of these high yield protocols are the enhanced reaction rates, greater selectivity and the experimental ease of manipulation. Among other reagents recently described in the literature on this eco-friendly green approach, the use of recyclable mineral oxides or supported reagents from our laboratory such as Fe(NO3)(3)-clay (clayfen), Cu(NO3)(2)-clay (claycop), NH4NO3-clay (clayan), NH2OH-clay, PhI(OAc)(2)-alumina, NaIO4-silica, CrO3-alumina, MnO2-silica, NaBH4-clay, etc. are highlighted in MW-promoted deprotection, condensation, cyclization, rearrangement, oxidation and reduction reactions including the rapid one-pot assembly of heterocyclic compounds from in situ generated intermediates.

引用

页码：43 / 55

页数：13

共 115 条

[81] Active manganese dioxide on silica: Oxidation of alcohols under solvent-free conditions using microwaves [J].

Varma, RS ;

Saini, RK ;

Dahiya, R .

TETRAHEDRON LETTERS, 1997, 38 (45) :7823-7824

[82]

Varma RS, 1997, SYNLETT, P857

[83] Solid state dethioacetalization using clayfen [J].

Varma, RS ;

Saini, RK .

TETRAHEDRON LETTERS, 1997, 38 (15) :2623-2624

[84] Microwave-assisted oxidation of alcohols under solvent-free conditions using clayfen [J].

Varma, RS ;

Dahiya, R .

TETRAHEDRON LETTERS, 1997, 38 (12) :2043-2044

[85] Microwave-assisted Henry reaction: Solventless synthesis of conjugated nitroalkenes [J].

Varma, RS ;

Dahiya, R ;

Kumar, S .

TETRAHEDRON LETTERS, 1997, 38 (29) :5131-5134

[86] MICROWAVE-ASSISTED DEACETYLATION ON ALUMINA - A SIMPLE DEPROTECTION METHOD [J].

VARMA, RS ;

VARMA, M ;

CHATTERJEE, AK .

JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1, 1993, (09) :999-1000

[87] ALUMINA-MEDIATED CLEAVAGE OF T-BUTYLDIMETHYLSILYL ETHERS [J].

VARMA, RS ;

LAMTURE, JB ;

VARMA, M .

TETRAHEDRON LETTERS, 1993, 34 (19) :3029-3032

[88] Solid state regeneration of ketones from oximes on wet silica supported sodium periodate using microwaves [J].

Varma, RS ;

Dahiya, R ;

Saini, RK .

TETRAHEDRON LETTERS, 1997, 38 (51) :8819-8820

[89] Wet alumina supported chromium(VI) oxide: Selective oxidation of alcohols in solventless system [J].

Varma, RS ;

Saini, RK .

TETRAHEDRON LETTERS, 1998, 39 (12) :1481-1482

[90] Iodobenzene diacetate on alumina: Rapid oxidation of alcohols to carbonyl compounds in solventless system using microwaves [J].

Varma, RS ;

Dahiya, R ;

Saini, RK .

TETRAHEDRON LETTERS, 1997, 38 (40) :7029-7032

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