Clinicopathologic and Immunohistochemical Findings from Autopsy of Patient with COVID-19, Japan

被引：109

作者：

Adachi, Takuya ^{[1
]}

Chong, Ja-Mun ^{[1
]}

Nakajima, Noriko ^{[2
]}

Sano, Masahiro ^{[1
]}

Yamazaki, Jun ^{[1
]}

Miyamoto, Ippei ^{[1
]}

Nishioka, Haruka ^{[1
]}

Akita, Hidetaka ^{[1
]}

Sato, Yuko ^{[2
]}

Kataoka, Michiyo ^{[2
]}

Katano, Harutaka ^{[2
]}

Tobiume, Minoru ^{[2
]}

Sekizuka, Tsuyoshi ^{[2
]}

Itokawa, Kentaro ^{[2
]}

Kuroda, Makoto ^{[2
]}

Suzuki, Tadaki ^{[2
]}

机构：

[1] Toshima Hosp, Tokyo, Japan

[2] Natl Inst Infect Dis, Tokyo, Japan

来源：

EMERGING INFECTIOUS DISEASES | 2020年 / 26卷 / 09期

关键词：

ACUTE RESPIRATORY SYNDROME; SYNDROME SARS; PATHOLOGY;

D O I：

10.3201/eid2609.201353

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

071005 [微生物学]; 100108 [医学免疫学];

摘要：

An autopsy of a patient in Japan with coronavirus disease indicated pneumonia lung pathology, manifested as diffuse alveolar damage. We detected severe acute respiratory syndrome coronavirus 2 antigen in alveolar epithelial cells and macrophages. Coronavirus disease is essentially a lower respiratory tract disease characterized by direct viral injury of alveolar epithelial cells.

引用

页码：2157 / 2161

页数：5

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