Replication, recombination, and repair: Going for the gold

被引:42
作者
Klein, HL [1 ]
Kreuzer, KN
机构
[1] NYU, Sch Med, Dept Biochem, New York, NY 10016 USA
[2] Duke Univ, Med Ctr, Dept Biochem, Durham, NC 27710 USA
关键词
D O I
10.1016/S1097-2765(02)00493-8
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
DNA recombination is now appreciated to be integral to DNA replication and cell survival. Recombination allows replication to successfully maneuver through the roadblocks of damaged or collapsed replication forks. The signals and controls that permit cells to transition between replication and recombination modes are now being identified.
引用
收藏
页码:471 / 480
页数:10
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