Colorimetric Protein Sensing Using Catalytically Amplified Sensor Arrays

被引：101

作者：

Li, Xiaoning ^{[1
]}

Wen, Fang ^{[2
]}

Creran, Brian ^{[1
]}

Jeong, Youngdo ^{[1
]}

Zhang, Xinrong ^{[2
]}

Rotello, Vincent M. ^{[1
]}

机构：

[1] Univ Massachusetts, Dept Chem, Amherst, MA 01003 USA

[2] Tsinghua Univ, Dept Chem, Beijing Key Lab Analyt Methods & Instrumentat, Beijing 100084, Peoples R China

来源：

SMALL | 2012年 / 8卷 / 23期

关键词：

protein sensing; colorimetry; sensor arrays; iron oxide nanoparticles; ROLLING CIRCLE AMPLIFICATION; GOLD NANOPARTICLES; GLUCOSE DETECTION; RECEPTORS; POLYNUCLEOTIDES; IDENTIFICATION; MICROARRAYS; TONGUE; CANCER; PROBES;

D O I：

10.1002/smll.201201549

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Catalytically active iron oxide nanoparticles are used as recognition elements and signal amplifiers for the array-based colorimetric sensing of proteins. Interactions between cationic monolayers on the Fe3O 4 NPs and analyte proteins differentially modulates the peroxidase-like activity of Fe3O4 NPs, affording catalytically amplified colorimetric signal patterns that enable the detection and identification of proteins at 50 nM. Copyright © 2012 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

引用

页码：3589 / 3592

页数：4

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