The N-terminal Z repeat 5 of connectin/titin binds to the C-terminal region of alpha-actinin

被引：65

作者：

Ohtsuka, H ^{[1
]}

Yajima, H ^{[1
]}

Maruyama, K ^{[1
]}

Kimura, S ^{[1
]}

机构：

[1] CHIBA UNIV,FAC SCI,DEPT BIOL,CHIBA 263,JAPAN

来源：

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS | 1997年 / 235卷 / 01期

关键词：

D O I：

10.1006/bbrc.1997.6534

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Connectin/titin, a 3000 kDa protein, links the Z line to the myosin filament in striated muscle sarcomeres. Using the yeast two-hybrid system, the present work shows that the N-terminal Z repeat 5 region (amino acids 447-472) of connectin binds to the C-terminal region (amino acids 825-897) of alpha-actinin, the main constituent of the Z line. (C) 1997 Academic Press.

引用

页码：1 / 3

页数：3

共 13 条

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