Synthesis and properties of (6,7-dimethoxy-4-coumaryl)alanine: A fluorescent peptide label

被引:16
作者
Bennett, FA [1 ]
Barlow, DJ [1 ]
Dodoo, ANO [1 ]
Hider, RC [1 ]
Lansley, AB [1 ]
Lawrence, MJ [1 ]
Marriott, C [1 ]
Bansal, SS [1 ]
机构
[1] Kings Coll London, Dept Pharm, London SW3 6LX, England
基金
英国医学研究理事会;
关键词
D O I
10.1006/abio.1999.4081
中图分类号
Q5 [生物化学];
学科分类号
071010 ; 081704 ;
摘要
The synthesis of racemic and L-(6,7-dimethoxy-4-coumaryl)alanine (Dmca) is described and some spectral and physicochemical properties are reported. The utility of Dmca as a highly sensitive and specific label for the quantitative detection of synthetic peptides in HPLC and in minimal essential media (MEM) is also described. (C) 1999 Academic Press.
引用
收藏
页码:15 / 23
页数:9
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