A general synthetic route towards bastadins. Part 1. Synthesis of the eastern part of bastadins 4-16

被引：10

作者：

Couladouros, EA

Moutsos, VI

机构：

[1] Agr Univ Athens, Dept Chem, Athens 11855, Greece

[2] NCSR Demokritos, Organ & Bioorgan Chem Lab, Athens 15310, Greece

来源：

TETRAHEDRON LETTERS | 1999年 / 40卷 / 38期

关键词：

bastadins; iodonium salt; synthesis; natural products; alpha-keto-acids; alpha-oximino-acids;

D O I：

10.1016/S0040-4039(99)01429-X

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A general synthetic route for the construction of the eastern part of the macrocyclic bastadins 4-16 is presented. The brominated biaryl ethers are synthesized using the iodonium salt method. The synthesis is accomplished within 18 steps in 15.5% overall yield. (C) 1999 Elsevier Science Ltd. All rights reserved.

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页码：7023 / 7026

页数：4

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