Preparation of cytocompatible luminescent and magnetic nanohybrids based on ZnO, Zn0.95Ni0.05O and core@shell ZnO@Fe2O3 polymer grafted nanoparticles for biomedical imaging

被引：10

作者：

Balti, I. ^{[1
,2
]}

Barrere, A. ^{[3
]}

Gueguen, V. ^{[3
]}

Poussard, L. ^{[3
]}

Pavon-Djavid, G. ^{[3
]}

Meddahi-Pelle, A. ^{[3
]}

Rabu, P. ^{[4
]}

Smiri, L. S. ^{[1
]}

Jouini, N. ^{[2
]}

Chaubet, F. ^{[3
]}

机构：

[1] Univ Carthage, Dept Chim, Unite Rech UR11ES30, Fac Sci Bizerte, Jarzouna 7021, Tunisia

[2] Univ Paris 13, LSPM, CNRS UPR 3407, Inst Galilee, F-93430 Villetaneuse, France

[3] Univ Paris 13, Lab Bioingn Polymeres Cardiovasc, Inserm U698, Inst Galilee, F-93430 Villetaneuse, France

[4] CNRS UDS, IPCMS UMR7504, Dept Chim Mat Inorgan, Strasbourg 2, France

来源：

JOURNAL OF NANOPARTICLE RESEARCH | 2012年 / 14卷 / 12期

关键词：

Nanoparticles; Zinc oxide; SI-ATRP; Poly(sodium-4-styrenesulfonate); Poly(sodium-4-styrenesulfonate-co-sodium methacrylate); Cytotoxicity; TRANSFER-RADICAL-POLYMERIZATION; OXIDE NANOPARTICLES; HYBRID NANOSTRUCTURES; OPTICAL-PROPERTIES; ENERGY; CELLS; PHOTOLUMINESCENCE; SEPARATION; INDUCTION; STYRENE;

D O I：

10.1007/s11051-012-1266-x

中图分类号：

O6 [化学];

学科分类号：

070301 [无机化学];

摘要：

ZnO, Zn0.95Ni0.05O and core@shell ZnO@c-Fe2O3 nanoparticles (NPs) have been prepared by forced hydrolysis in polyol medium and then coated via the "grafting from" approach with poly(sodium-4-styrenesulfonate) and poly(sodium-4-styrenesulfonate-co-sodium methacrylate) in the case of ZnO. The surface-initiated atom transfer radical polymerization occurred from the surface-functionalized NPs with alpha-bromoisobutyric acid as initiator. The polymer chains were grown from the surface to yield hybrid NPs with a 1-3-nm thick organic shell. FT-IR, TGA and electron microscopy evidenced the presence of a polymer layer on the surface of NPs. Magnetic and optical properties of bare and coated NPs have been measured. Eventually, the weak cytotoxicity of coated NPs on human endothelial cell allows considering their potentialities as new tools for nanomedicine and biomedical imaging.

引用

页数：15

共 57 条

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