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Microbial pathogenesis: Genomics and beyond

被引：130
作者：
Strauss, EJ
Falkow, S
机构：
[1] Dept. of Microbiology and Immunology, Stanford University, School of Medicine, Stanford
来源：
SCIENCE | 1997年 / 276卷 / 5313期
关键词：
D O I：
10.1126/science.276.5313.707
中图分类号：
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号：
07 ; 0710 ; 09 ;
摘要：
The growing number of complete microbial genome sequences provides a powerful tool for studying the biology of microorganisms. In combination with assays for function, genomic-based approaches can facilitate efficient and directed research strategies to elucidate mechanisms of bacterial pathogenicity. As genomic information accrues, the challenge remains to construct a picture of the biology that accurately reflects how individual genes collaborate to create the complex world of microbial specialization.
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页码：707 / 712
页数：6
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