Factor Xa - a promising target for drug development

被引：43

作者：

Kaiser, B ^{[1
]}

机构：

[1] Univ Jena, Ctr Vasc Biol & Med Erfurt, D-99089 Erfurt, Germany

来源：

CELLULAR AND MOLECULAR LIFE SCIENCES | 2002年 / 59卷 / 02期

关键词：

D O I：

10.1007/s00018-002-8415-9

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

[No abstract available]

引用

页码：189 / 192

页数：4

共 40 条

[1] Factor Xa inhibitors
Al-Obeidi, F
Ostrem, JA
[J]. EXPERT OPINION ON THERAPEUTIC PATENTS, 1999, 9 (07) : 931 - 953
[2] ALTIERI DC, 1994, J BIOL CHEM, V269, P3139
[3] ALTIERI DC, 1990, J IMMUNOL, V145, P246
[4] BAUER K, 2001, THROMB HAEMOST S, pOC46
[5] Recent advances in Factor Xa inhibitors
Betz, A
[J]. EXPERT OPINION ON THERAPEUTIC PATENTS, 2001, 11 (06) : 1007 - 1017
[6] Factor Xa is a fibroblast mitogen via binding to effector-cell protease receptor-1 and autocrine release of PDGF
Blanc-Brude, OP
Chambers, RC
Leoni, P
Dik, WA
Laurent, GJ
[J]. AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY, 2001, 281 (02): : C681 - C689
[7] STRUCTURE-ACTIVITY RELATIONSHIP IN HEPARIN - A SYNTHETIC PENTASACCHARIDE WITH HIGH-AFFINITY FOR ANTI-THROMBIN-III AND ELICITING HIGH ANTI-FACTOR-XA ACTIVITY
CHOAY, J
PETITOU, M
LORMEAU, JC
SINAY, P
CASU, B
GATTI, G
[J]. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 1983, 116 (02) : 492 - 499
[8] A synthetic factor-Xa inhibitor (ORG31540/SR9017A) as an adjunct to fibrinolysis in acute myocardial infarction - The PENTALYSE study
Coussement, PK
Bassand, JP
Convens, C
Vrolix, M
Boland, J
Grollier, G
Michels, R
Vahanian, A
Vanderheyden, M
Rupprecht, HJ
Van de Werf, F
[J]. EUROPEAN HEART JOURNAL, 2001, 22 (18) : 1716 - 1724
[9] DEPASSE F, 2001, THROMB HAEMOST S, pP3098
[10] Mechanism of heparin activation of antithrombin:: Evidence for an induced-fit model of allosteric activation involving two interaction subsites
Desai, UR
Petitou, M
Björk, I
Olson, ST
[J]. BIOCHEMISTRY, 1998, 37 (37) : 13033 - 13041

← 1 2 3 4 →