Chromatographic explanation for the side-wall induced band broadening in pressure-driven and shear-driven flows through channels with a high aspect-ratio rectangular cross-section

被引:29
作者
Desmet, G [1 ]
Baron, GV [1 ]
机构
[1] Free Univ Brussels, Dept Chem Engn, B-1050 Brussels, Belgium
关键词
laminar flow; band broadening; microchannels;
D O I
10.1016/S0021-9673(01)01546-1
中图分类号
Q5 [生物化学];
学科分类号
071010 ; 081704 ;
摘要
Based on a simple, chromatography-based analogy, a quantitatively exact explanation for the strong additional band broadening induced by the presence of the side-walls in flow channels with a large aspect-ratio rectangular cross-section is,given and validated for two different flow types: pressure-driven and shear-driven flow. (C) 2002 Elsevier Science B.V. All rights reserved.
引用
收藏
页码:51 / 58
页数:8
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