An efficient chemoenzymatic route to dihydroxy acetone phosphate from glycidol for the in situ aldolase-mediated synthesis of monosaccharides

被引：22

作者：

Charmantray, F

Dellis, P

Samreth, S

Hecquet, L

机构：

[1] Univ Clermont Ferrand, CNRS, UMR 6504, Lab SEESIB, F-63117 Aubiere, France

[2] Synkem SAS, F-21300 Chenove, France

[3] Fournier Pharma, F-21121 Daix, France

来源：

TETRAHEDRON LETTERS | 2006年 / 47卷 / 19期

关键词：

DHAP; multienzymatic synthesis; aldolase; C-C bond formation;

D O I：

10.1016/j.tetlet.2006.03.036

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

We report a new two-step procedure that uses inexpensive rac-glycidol to obtain valuable dihydroxyacetone phosphate (DHAP), a building block for the synthesis of monosaccharide analogues. (c) 2006 Elsevier Ltd. All rights reserved.

引用

页码：3261 / 3263

页数：3

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