Biological properties of the angiotensin peptides other than angiotensin II: implications for hypertension and cardiovascular diseases

被引：57

作者：

Cesari, M ^{[1
]}

Rossi, GP ^{[1
]}

Pessina, AC ^{[1
]}

机构：

[1] Univ Hosp, Clin Med 4, Dept Clin & Expt Med, I-35126 Padua, Italy

来源：

JOURNAL OF HYPERTENSION | 2002年 / 20卷 / 05期

关键词：

angiotensin fragments; hypertension; cardiovascular disease;

D O I：

10.1097/00004872-200205000-00002

中图分类号：

R6 [外科学];

学科分类号：

1002 ; 100210 ;

摘要：

Several peptides of the RAS other than angiotensin (1-8) have been identified. They are generally referred as 'angiotensin fragments': Ang (2-8), Ang (3-8) and Ang (1 7) and have been detected in human tissues. There is evidence that they may play a functional role in humans by acting in concert with angiotensin (1-8) and aldosterone. Available knowledge on the pathways leading to synthesis and degradation of angiotensin fragments, as well as on their interactions with receptors and on their possible role in cardiovascular homeostasis and disease are reviewed. J Hypertens 20:793-799 (C) 2002 Lippincott Williams Wilkins.

引用

页码：793 / 799

页数：7

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