Multiple surface plasmon spectroscopy for study of biomolecular systems

被引：70

作者：

Adam, P ^{[1
]}

Dostálek, J ^{[1
]}

Homola, J ^{[1
]}

机构：

[1] Acad Sci Czech Republ, Inst Radio Engn & Elect, Prague 18251, Czech Republic

来源：

SENSORS AND ACTUATORS B-CHEMICAL | 2006年 / 113卷 / 02期

关键词：

surface plasmon; diffraction grating; surface plasmon resonance; sensor;

D O I：

10.1016/j.snb.2005.07.029

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

We report a new approach to surface plasmon resonance (SPR) biosensing based on spectroscopy of multiple surface plasmons on a special multi-diffractive grating coupler. In this approach, the binding event at a surface of the SPR grating coupler is simultaneously observed by surface plasmons of different wavelengths, which makes it possible to determine binding-induced changes in the refractive index distribution at the sensor surface. We demonstrate the potential of this new concept in a model experiment in which three-surface plasmon spectroscopy is used to determine background refractive index variations and changes in the thickness and refractive index of a bovine serum albumin multi-layer grown on the surface of the SPR grating coupler. (c) 2005 Elsevier B.V. All rights reserved.

引用

页码：774 / 781

页数：8

共 24 条

[21] Optical anisotropy in lipid bilayer membranes: Coupled plasmon-waveguide resonance measurements of molecular orientation, polarizability, and shape [J].

Salamon, Z ;

Tollin, G .

BIOPHYSICAL JOURNAL, 2001, 80 (03) :1557-1567

[22]

Snyder A.W., 1983, OPTICAL WAVEGUIDE TH

[23] Refractive index and thickness determination of monolayers by multi mode waveguide coupled surface plasmons [J].

Weisser, M ;

Menges, B ;

Mittler-Neher, S .

SENSORS AND ACTUATORS B-CHEMICAL, 1999, 56 (03) :189-197

[24] Estimation of organic molecular film structures using surface-plasmon resonance spectroscopy [J].

Zhou, M ;

Otomo, A ;

Yokoyama, S ;

Mashiko, S .

THIN SOLID FILMS, 2001, 393 (1-2) :114-118

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