An insulin-sensing sugar-based fluorescent hydrogel

被引:73
作者
Bhuniya, S [1 ]
Kim, BH [1 ]
机构
[1] Pohang Univ Sci & Technol, Dept Chem, Pohang 790784, South Korea
关键词
D O I
10.1039/b516632b
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
We have prepared a small library of amphiphiles, each comprising a polar carbohydrate head group attached through an N-terminal amino acid to a nonpolar pyrene tail group. One of these derivatives is sensitive to the presence of insulin in aqueous media.
引用
收藏
页码:1842 / 1844
页数:3
相关论文
共 52 条
[21]   Self-assembly of a sugar-based gelator in water: Its remarkable diversity in gelation ability and aggregate structure [J].
Jung, JH ;
John, G ;
Masuda, M ;
Yoshida, K ;
Shinkai, S ;
Shimizu, T .
LANGMUIR, 2001, 17 (23) :7229-7232
[22]   Molecular design of "super" hydrogelators: Understanding the gelation process of azobenzene-based sugar derivatives in water [J].
Kobayashi, H ;
Friggeri, A ;
Koumoto, K ;
Amaike, M ;
Shinkai, S ;
Reinhoudt, DN .
ORGANIC LETTERS, 2002, 4 (09) :1423-1426
[23]   Glucose-induced release of glycosylpoly(ethylene glycol) insulin bound to a soluble conjugate of concanavalin A [J].
Liu, F ;
Song, SC ;
Mix, D ;
Baudys, M ;
Kim, SW .
BIOCONJUGATE CHEMISTRY, 1997, 8 (05) :664-672
[24]   Novel class of saccharide-based organogelators: glucofuranose derivatives as one of the smallest and highly efficient gelators [J].
Luboradzki, R ;
Pakulski, Z .
TETRAHEDRON, 2004, 60 (21) :4613-4616
[25]   Using pH-sensitive hydrogels containing cubane as a crosslinking agent for oral delivery of insulin [J].
Mahkam, M .
JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART B-APPLIED BIOMATERIALS, 2005, 75B (01) :108-112
[26]  
Maitra U, 2001, ANGEW CHEM INT EDIT, V40, P2281, DOI 10.1002/1521-3773(20010618)40:12<2281::AID-ANIE2281>3.0.CO
[27]  
2-L
[28]   Diagnosing insulin resistance in the general population [J].
McAuley, KA ;
Williams, SM ;
Mann, JI ;
Walker, RJ ;
Lewis-Barned, NJ ;
Temple, LA ;
Duncan, AW .
DIABETES CARE, 2001, 24 (03) :460-464
[29]   Gemini-induced columnar jointing in vitreous ice. Cryo-HRSEM as a tool for discovering new colloidal morphologies [J].
Menger, FM ;
Zhang, H ;
Caran, KL ;
Seredyuk, VA ;
Apkarian, RP .
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2002, 124 (07) :1140-1141
[30]   Anatomy of a gel. Amino acid derivatives that rigidify water at submillimolar concentrations [J].
Menger, FM ;
Caran, KL .
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2000, 122 (47) :11679-11691