alpha,alpha-difluoroallyl carbanion: Indium-mediation in its facile coupling with aldehydes

被引：41

作者：

Kirihara, M ^{[1
]}

Takuwa, T ^{[1
]}

Takizawa, S ^{[1
]}

Momose, T ^{[1
]}

机构：

[1] TOYAMA MED & PHARMACEUT UNIV,FAC PHARMACEUT SCI,TOYAMA 93001,JAPAN

来源：

TETRAHEDRON LETTERS | 1997年 / 38卷 / 16期

关键词：

D O I：

10.1016/S0040-4039(97)00480-2

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Indium-mediated coupling of aldehydes with 3-bromo-3,3-difluoropropene gives 1-substituted-2,2-difluorobut-3-en-1-ols in high yields at room temperature. The coupling takes place at the gem-difluorocarbon selectively. Ketones are inert under the conditions examined. (C) 1997 Elsevier Science Ltd.

引用

页码：2853 / 2854

页数：2

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