Blood pressure variability as a risk factor

被引：36

作者：

Parati, G ^{[1
]}

Mancia, G ^{[1
]}

机构：

[1] Univ Milano Bicocca, S Luca Hosp, Ist Auxol Italiano, Dept Internal Med, I-20149 Milan, Italy

来源：

BLOOD PRESSURE MONITORING | 2001年 / 6卷 / 06期

关键词：

blood pressure variability; essential hypertension; ambulatory blood pressure monitoring; organ damage; smoothness index;

D O I：

10.1097/00126097-200112000-00014

中图分类号：

R6 [外科学];

学科分类号：

1002 ; 100210 ;

摘要：

Blood pressure variability is clinically relevant because of the evidence that the degree of blood pressure fluctuation may independently contribute to organ damage and to the cardiovascular risk of hypertensive patients. This review will focus on the evidence available to support this concept. As such, data obtained from cross-sectional studies, longitudinal studies in humans and experimental studies in animals will be discussed. The possibility of antagonizing an excessive degree of blood pressure variability by administering drugs to provide a long-lasting and smooth anti hypertensive action will also be discussed, as will the usefulness of mathematical indices aimed at quantifying the homogeneity of the blood pressure reduction by treatment. (C) 2001 Lippincott Williams Wilkins.

引用

页码：341 / 347

页数：7

共 38 条

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