Poly(A) tail synthesis and regulation: recent structural insights

被引：21

作者：

Hall, TMT ^{[1
]}

机构：

[1] NIEHS, Struct Biol Lab, NIH, Res Triangle Pk, NC 27709 USA

来源：

CURRENT OPINION IN STRUCTURAL BIOLOGY | 2002年 / 12卷 / 01期

关键词：

D O I：

10.1016/S0959-440X(02)00293-2

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Polyadenylation at the 3' ends of mRNAs is critical to the translation and stability of the messages. Recently determined structures of poly(A) polymerase, U 1 A and domains of the poly(A)-binding protein provide a framework for understanding the synthesis and regulation of the poly(A) tail.

引用

页码：82 / 88

页数：7

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