Daptomycin-rifampin for a recurrent MRSA joint infection unresponsive to vancomycin-based therapy

被引：32

作者：

Burns, CA ^{[1
]}

机构：

[1] Ocala Reg Med Ctr, Ocala, FL 34478 USA

来源：

SCANDINAVIAN JOURNAL OF INFECTIOUS DISEASES | 2006年 / 38卷 / 02期

关键词：

D O I：

10.1080/00365540500277292

中图分类号：

R51 [传染病];

学科分类号：

100401 ;

摘要：

A 54-y-old morbidly obese male presented with methicillin-resistant Staphylococcus aureus ( MRSA) bacteremia secondary to chronic right hip arthroplasty infection. Bacteremia persisted despite prolonged vancomycin-based therapy ( MIC <= 1 mu g/ml) and prosthetic removal. Adding daptomycin-rifampin resolved bacteremia within 48 h; hip cultures remained negative post-discharge. This case describes alternative treatment for chronic MRSA infections.

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页码：133 / 136

页数：4

相关论文

共 18 条

[11] Once-daily dosing in dogs optimizes daptomycin safety [J].

Oleson, FB ;

Berman, CL ;

Kirkpatrick, JB ;

Regan, KS ;

Lai, JJ ;

Tally, FP .

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 2000, 44 (11) :2948-2953

[12] Daptomycin synergy with rifampicin and ampicillin against vancomycin-resistant enterococci [J].

Rand, KH ;

Houck, H .

JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, 2004, 53 (03) :530-532

[13] Prospective evaluation of the effect of an aminoglycoside dosing regimen on rates of observed nephrotoxicity and ototoxicity [J].

Rybak, MJ ;

Abate, BJ ;

Kang, SL ;

Ruffing, MJ ;

Lerner, SA ;

Drusano, GL .

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 1999, 43 (07) :1549-1555

[14] Relationship of MIC and bactericidal activity to efficacy of vancomycin for treatment of methicillin-resistant Staphylococcus aureus bacteremia [J].

Sakoulas, G ;

Moise-Broder, PA ;

Schentag, J ;

Forrest, A ;

Moellering, RC ;

Eliopoulos, GM .

JOURNAL OF CLINICAL MICROBIOLOGY, 2004, 42 (06) :2398-2402

[15] Emergence of vancomycin resistance in Staphylococcus aureus [J].

Smith, TL ;

Pearson, ML ;

Wilcox, KR ;

Cruz, C ;

Lancaster, MV ;

Robinson-Dunn, B ;

Tenover, FC ;

Zervos, MJ ;

Band, JD ;

White, E ;

Jarvis, WR .

NEW ENGLAND JOURNAL OF MEDICINE, 1999, 340 (07) :493-501

[16] Daptomycin activity and spectrum: a worldwide sample of 6737 clinical Gram-positive organisms [J].

Streit, JM ;

Jones, RN ;

Sader, HS .

JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, 2004, 53 (04) :669-674

[17]

TAM VH, 1999, 39 INT C ANT AG CHEM

[18]

TSUJI BT, 2004, 44 ICAAC 30 OCT 2 NO, P1171