Bacterial invasion: The paradigms of enteroinvasive pathogens

被引:746
作者
Cossart, P
Sansonetti, PJ
机构
[1] Inst Pasteur, INSERM, U604, Unite Interact Bacteries Cellules, F-75015 Paris, France
[2] Inst Pasteur, Dept Biol Cellulaire & Infect, CNRS, U389,Unite Pathogenie Microbienne Mol, F-75015 Paris, France
关键词
D O I
10.1126/science.1090124
中图分类号
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号
07 ; 0710 ; 09 ;
摘要
Invasive bacteria actively induce their own uptake by phagocytosis in normally nonphagocytic cells and then either establish a protected niche within which they survive and replicate, or disseminate from cell to cell by means of an actin-based motility process. The mechanisms underlying bacterial entry, phagosome maturation, and dissemination reveal common strategies as well as unique tactics evolved by individual species to establish infection.
引用
收藏
页码:242 / 248
页数:7
相关论文
共 69 条
  • [31] Trafficking of the Salmonella vacuole in macrophages
    Holden, DW
    [J]. TRAFFIC, 2002, 3 (03) : 161 - 169
  • [32] A role for phosphoinositide 3-kinase in bacterial invasion
    Ireton, K
    Payrastre, B
    Chap, H
    Ogawa, W
    Sakaue, H
    Kasuga, M
    Cossart, P
    [J]. SCIENCE, 1996, 274 (5288) : 780 - 782
  • [33] Isberg RR, 2001, J CELL SCI, V114, P21
  • [34] Kagnoff MF, 2003, MICROBIAL PATHOGENESIS AND THE INTESTINAL EPITHELIAL CELL, P155
  • [35] Temporal regulation of Salmonella virulence effector function by proteasome-dependent protein degradation
    Kubori, T
    Galán, JE
    [J]. CELL, 2003, 115 (03) : 333 - 342
  • [36] Initial steps of Shigella infection depend on the cholesterol/sphingolipid raft-mediated CD44-IpaB interaction
    Lafont, F
    Van Nhieu, GT
    Hanada, K
    Sansonetti, P
    van der Goot, FG
    [J]. EMBO JOURNAL, 2002, 21 (17) : 4449 - 4457
  • [37] A role for α- and β-catenins in bacterial uptake
    Lecuit, M
    Hurme, R
    Pizarro-Cerdá, J
    Ohayon, H
    Geiger, B
    Cossart, P
    [J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2000, 97 (18) : 10008 - 10013
  • [38] Genetically-modified-animal models for human infections:: the Listeria paradigm
    Lecuit, M
    Cossart, P
    [J]. TRENDS IN MOLECULAR MEDICINE, 2002, 8 (11) : 537 - 542
  • [39] A transgenic model for listeriosis: Role of internalin in crossing the intestinal barrier
    Lecuit, M
    Vandormael-Pournin, S
    Lefort, J
    Huerre, M
    Gounon, P
    Dupuy, C
    Babinet, C
    Cossart, P
    [J]. SCIENCE, 2001, 292 (5522) : 1722 - 1725
  • [40] A single amino acid in E-cadherin responsible for host specificity towards the human pathogen Listeria monocytogenes
    Lecuit, M
    Dramsi, S
    Gottardi, C
    Fedor-Chaiken, M
    Gumbiner, B
    Cossart, P
    [J]. EMBO JOURNAL, 1999, 18 (14) : 3956 - 3963