Paternity probability when a relative of the father is an alleged father

被引:14
作者
Lee, JW
Lee, HS
Park, M
Hwang, JJ
机构
[1] Korea Univ, Dept Legal Med, Seoul, South Korea
[2] Eulji Med Coll, Dept Premed, Taejon, South Korea
关键词
forensic science; genetics; statistics; DNA; paternity; coancestry coefficient; genetic relationship;
D O I
10.1016/S1355-0306(99)72053-8
中图分类号
DF [法律]; D9 [法律]; R [医药、卫生];
学科分类号
0301 ; 10 ;
摘要
When scientists use DNA evidence in court, coancestry effects such as population structure and relatedness are usually ignored. In paternity cases, only if a particular man has the child's paternal allele at a certain locus, can he not be excluded in the paternity dispute. However, it is certainly true that close relatives will be far more likely to have the child's paternal allele than will random members of the reference population. In particular, the probability that the true father's brother has the paternal allele is very much greater than that for any other relationship. In this paper, the authors describe a method for inference in a case where the true father may be a relative of the alleged father. This paper also reports that most current methods overstate the probability that the alleged father is the father.
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页码:223 / 230
页数:8
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